For livestock breeding, bacteria, viruses, parasites and mycotoxins are four major hazards that must be guarded against at all times. Mycotoxins have brought serious hazards to the breeding of livestock and poultry. Despite increasingly more and more methods for controlling molds, how is a truly high-efficient product selected? Tuomei’an (Mold remover) serves as a most ideal mycotoxin remover. Different from adsorbent, Tuomei’an (Mold remover) is mixed into finished feed or raw feed by means of physical adsorption action, chemical passivation action and 3-D mesh-gel technology, removing mycotoxins by its action in the intestines. 

Tuomei’an (Mold remover) has a wide range of effectiveness, being capable of removing various molds. Evenly distributed in feed, it can play a role in removing molds both in feed and animal bodies, and also does no damage to nutrients in feed. As demonstrated by a great number of experiments on early weaned piglets, finishing pigs and lactating sows, this product can improve the body’s immunity and reduce the incidence of diseases of animals; increase feed intake and enhance growth speed; prevent the occurrence of breeding obstacles of sows, such as false heat, sterility, abortion & dead fetus and small litter size; decrease the diarrhea rate of piglets and increase their survival rate; advance the slaughter of fat pigs; eliminate hidden troubles caused by use of low-quality feed; protect the normal use of vaccine products for animals. Tuomei’an (Mold remover) not only acts as a super adsorbent of mycotoxins, but also contains unique bio-active components promoting animal immunity. It can rapidly get rid of immune inhibition while absorbing molds and removing toxins so as to promote the immunity of livestock and poultry. Therefore, it is a perfect solution of mycotoxin hazards.             

Mycotoxin is a toxin produced by a mold in raw materials and feed. These mycotoxins produced by molds in animal bodies will result in serious economic losses to intensive livestock and poultry producers.

In animal feed, the most common mycotoxins include: aflatoxins, ochratoxin A, Zearalenone (ZEA), vomiting toxin and so on.

Mycotoxin hazards to pig farms:

1. Reducing the nutritive value of feed and resulting in a shortage of nutrients ingested by pigs——a loss of vitamins, amino acids and fat energy by 20-50%.
2. Bringing about responses of clinical diseases：
3. Breeding obstacles：false heat, genital swelling, abortion & fatal fetus and lack of semen
4. Restricted feed intake: slow growth and delayed slaughter 
5. Multiple syndrome: diarrhea, respiratory diseases and Eperythrozoon blue ear disease…

6. Causing immune poisoning and lymphocyte necrosis——immune failure

Mode of action of Tuomei’an (Mold remover):

1. Contains various adsorptive clay minerals, silicates and chelating agents.
2. Forms stable compounds with mycotoxins and a variety of groups.
3. Reduces the bioavailability of mycotoxins in animal bodies so as to avoid being absorbed by the digestive tract. 
4. Prevents cells from encroachments by the oxidation of various groups.
5. Inhibits the growth of molds to prevent the reemergence of mycotoxins.
6. Utilizes the biochemical conversion action of specially fermented extracts to degrade

7. Zearalenone and all various types of trichothecene toxins, including T-2 toxin and HT-2 tonxi, into innoxious metabolites.

Mechanism of adsorbing mycotoxins by inorganic adsorbents 

Main characteristics of inorganic absorbents are shown below:

1. Automatically combine with aflatoxins and other fungus toxins in the body of livestock and poultry before jointly discharged from the body completely.
2. Select the adsorption of toxins without interference with the absorption of other nutrients, and improve the immunity and nutrient absorption of animals.
3. Deactivate toxins to be discharged from the body without any residue in the body, guaranteeing the normal development of livers and kidneys of animals and other important metabolic organs to obviously promote growth. 

4. Overcome the toxicity of Zearalenone (ZEA) to dams and embryos, protect embryonic development, increase the number of weaned litters and decrease maternal mortality rate.

Mechanism of Tuomei’an (Mold remover):
There are three types of sites binding Tuomei’an (Mold remover) and mycotoxins: 1 Surface passage; 2 Skin; 3 Side as a large-area chemical binding. A great surface of Tuomei’an (Mold remover) decides its so high adsorption of mycotoxins. The surface area of Tuomei’an (Mold remover) is 42 times that of Mannan oligosaccharide extracted by yeast cells, so its adsorption ability is 40 times that of ordinary aluminosilicate products. Tuomei’an (Mold remover) and mycotoxins bound together are uneasily separated in the animal body and rapidly discharged from the body.       

Therefore, Tuomei’an (Mold remover) won’t do damage to nutritive elements in feed while removing toxins, and moreover won’t affect the animal body in any way. 

Eliminating toxins in the body and reinforcing the body’s immunity

Tuomei’an (Mold remover) is capable of effectively eliminating toxins in the pig body. Its probiotics repel the attachment and colonization of harmful bacteria by virtue of space occupying effect, thereby greatly reducing the discharge of toxins both in the body and harmful bacteria, and alleviating the burden of detoxification and excretion of livers and kidneys. What’s more, Tuomei’an (Mold remover) can excite the development and improvement of intestinal mucosal immune system, effectively arresting the entry of toxins in the body into the blood circulation system; macrophage activity and enhanced vitality of natural killer (NK) cells can identify harmful bacteria at a high speed, engulfing and killing them. The promoted synthesis and secretion of SIGA (secretory immunoglobulin A) can effectively adsorb and remove lipopolysaccharide (endotoxin) of harmful bacteria, and reduce the sensitization of endotoxin to the intestines.       

Improved animal immune functions reinforce specific and nonspecific immune functions of the body simultaneously and make animals keep healthy conditions at all times. Therefore, the application of Tuomei’an (Mold remover) can reinforce efficacies of antibiotics in feed and drinking water as well as injected, promote the secretion of antibiotic residue in livers and kidneys, and reduce the toxicity of drugs and antibiotics as well as antibacterial resistance of bacteria; meanwhile, reinforce immune effects of vaccines and reduce stress reaction of vaccine injection.    

Tuomei’an (Mold remover) produces a desirable effect on pigs in poor conditions, so the application of Tuomei’an (Mold remover) can also improve the uniformity of herds.

Recommended usage and dosage of Tuomei’an (Mold remover)

1.  Long-time use of 500g/t can obviously prevent encroachments of toxins and promote feed intake and development of pigs. It is recommended to apply it all the year round, particularly between May and August as well as between November and February.  
   
2. When pigs have been infected, or feed or raw materials have obvious changes in color, immediate treatment is required: 
   At the early stage of 3-5 days, 2-3 kg /t applied, 5-10 days, 1.5 kg /t applied，10-15 days，1 kg /t applied; at the late stage, 0.5 kg /t for 10 consecutive days. 
   
3.  The application of Tuomei’an (Mold remover) won’t do damage to nutrients in feed as a result of adsorption.